Objectives
The overarching goal of AVITHRAPID is to develop novel broad-spectrum antivirals providing additional therapeutic options for current and future epidemics and pandemics based on existent substances with proven efficacy against drug targets using a rational pre-clinical drug discovery workflow.
By coordinating cutting-edge capacities and expertise already available in Europe AVITHRAPID will focus on specific objectives:
- Supporting pandemic preparedness by provision of novel approaches for the development of antivirals using sophisticated computational methods in combination with experimental validation.
- Joint development and optimization of pre-clinical candidates based on an available set of small molecules addressing various viral targets with a focus on broad-spectrum applicability
- Establish a complete pre-clinical drug discovery pipeline based on the research activities within AVITHRAPID, that allows to react rapidly in case of novel viral infections with pandemic potential.